Yuxuan Miao, PhD

Yuxuan (Phoenix) Miao’s research focuses on understanding how normal and cancerous epithelial tissue adapt to inflammation, with a special interest in dissecting how stem cells residing in these tissues interact with the immune system to maintain normal tissue fitness and achieve cancer immune evasion.

Rockefeller University
New York, NY
Postdoc - Stem cell and cancer biology
2020

Duke University School of Medicine
Durham, NC
PhD - Immunology
2015

Beijing Institute of Technology
Beijing, China
B.S. - Biotechnology
2008

Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer.
Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer. NPJ Precis Oncol. 2024 May 23; 8(1):114.
PMID: 38783041

CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment.
CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment. Immunity. 2024 May 14; 57(5):1071-1086.e7.
PMID: 38677291

Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium.
Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium. Cancer Immunol Res. 2023 12 01; 11(12):1571-1577.
PMID: 37906619

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer.
SFyNCS detects oncogenic fusions involving non-coding sequences in cancer. Nucleic Acids Res. 2023 Oct 13; 51(18):e96.
PMID: 37638762

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer.
SFyNCS detects oncogenic fusions involving non-coding sequences in cancer. bioRxiv. 2023 Apr 06.
PMID: 37066382

A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections.
A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. Nat Immunol. 2020 06; 21(6):671-683.
PMID: 32424366

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices.
NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices. Nat Cell Biol. 2020 06; 22(6):640-650.
PMID: 32393888

Stem cell-driven lymphatic remodeling coordinates tissue regeneration.
Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 12 06; 366(6470):1218-1225.
PMID: 31672914

Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells.
Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. Cell. 2019 05 16; 177(5):1172-1186.e14.
PMID: 31031009

Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.
Miao Y, Bist P, Wu J, Zhao Q, Li QJ, Wan Y, Abraham SN. Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium. . 2017 Sep 13; 22(3):330-342.e4.
PMID: 28910634

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NCI K99/R00 Pathway to Independence Award
Rockefeller University
2019 - 2023

Robertson Therapeutic Development Foundation Award
Rockefeller University
2019 - 2020

Jane Coffin Childs Fellowship
Rockefeller University
2016 - 2019

Mitchell Meritorious Research Award
Duke University
2015

Duke Chancellor Award
Duke University
2009