Faculty

Yuxuan Miao, PhD

Yuxuan (Phoenix) Miao’s research focuses on understanding how normal and cancerous epithelial tissue adapt to inflammation, with a special interest in dissecting how stem cells residing in these tissues interact with the immune system to maintain normal tissue fitness and achieve cancer immune evasion.

Rockefeller University
New York, NY
Postdoc - Stem cell and cancer biology
2020

Duke University School of Medicine
Durham, NC
PhD - Immunology
2015

Beijing Institute of Technology
Beijing, China
B.S. - Biotechnology
2008

Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma.
Comprehensive multi-omic dissection and AI-prioritized target identification in inverted papilloma-associated sinonasal squamous cell carcinoma. NPJ Precis Oncol. 2026 Jul 10.
PMID: 42432132

Comparative single cell analysis of wound and cancer identifies the metabolic dialogues between tumor initiating stem cells and macrophages.
Comparative single cell analysis of wound and cancer identifies the metabolic dialogues between tumor initiating stem cells and macrophages. bioRxiv. 2026 Apr 06.
PMID: 41993506

Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche.
Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche. Cancer Cell. 2026 Jan 12; 44(1):94-111.e11.
PMID: 41349542

Early Dynamics of Circulating Tumor HPV-DNA with Neoadjuvant Chemotherapy and Response-Adapted De-escalation in Human Papillomavirus-Associated Oropharyngeal Cancer.
Early Dynamics of Circulating Tumor HPV-DNA with Neoadjuvant Chemotherapy and Response-Adapted De-escalation in Human Papillomavirus-Associated Oropharyngeal Cancer. Clin Cancer Res. 2025 Aug 01; 31(15):3150-3159.
PMID: 40423530

PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands.
PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands. J Exp Clin Cancer Res. 2025 Jan 11; 44(1):11.
PMID: 39794830

Circulating tumor DNA in head and neck squamous cell carcinoma-current status and future prospects.
Circulating tumor DNA in head and neck squamous cell carcinoma-current status and future prospects. Acad Oncol. 2024; 1(2).
PMID: 39867572

Stemness in solid malignancies: coping with immune attack.
Stemness in solid malignancies: coping with immune attack. Nat Rev Cancer. 2025 Jan; 25(1):27-40.
PMID: 39455862

Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer.
Acquired resistance to immunotherapy and chemoradiation in MYC amplified head and neck cancer. NPJ Precis Oncol. 2024 May 23; 8(1):114.
PMID: 38783041

CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment.
CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment. Immunity. 2024 05 14; 57(5):1071-1086.e7.
PMID: 38677291

Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium.
Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium. Cancer Immunol Res. 2023 12 01; 11(12):1571-1577.
PMID: 37906619

View All Publications

NCI K99/R00 Pathway to Independence Award
Rockefeller University
2019 - 2023

Robertson Therapeutic Development Foundation Award
Rockefeller University
2019 - 2020

Jane Coffin Childs Fellowship
Rockefeller University
2016 - 2019

Mitchell Meritorious Research Award
Duke University
2015

Duke Chancellor Award
Duke University
2009