Wei Du, Ph.D.


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Li, B., Gordon, GM., Du, CH., Xu, J., and Du, W. (2010) Specific killing of Rb mutant cancer cells by inactivating TSC2. Cancer Cell. 17, 469–480. NIHMSID #196476.

Li, B, Wang, CZ, He, TC, Yuan, CS, Du, W. (2010) Antioxidants potentiate American ginseng-induced apoptosis in colorectal cancer cells. Cancer Lett. 289, 62-70. [Epub 2009 Aug 27]. NIHMSID: NIHMS141750.

Steele, L., Sukhanova, MJ., Xu, J., Gordon, GM., Huang, Y, Yu, L., and Du, W. (2009) Rhinoceros and Retinoblastoma family protein regulate Delta expression during photoreceptor R8 determination. Dev Biol. 335, 228–236. NIHMSID: NIHMS144795.

Tanaka-Matakatsu, M., Xu, J., Cheng, L., and Du, W. (2009) Regulation of apoptosis of rbf mutant cells during Drosophila development. Dev Biol. 326, 347-56. NIHMSID # 84081.

Sukhanova, MJ and Du, W. (2008) Control of Cell Cycle Entry and Exiting from the Second Mitotic Wave in the Drosophila Developing Eye. BMC Developmental Biology. 8, 7. PMCID: PMC2267170.

Deb,DK, Matakatsu, MT, Jones, L., Richardson, HE, and Du, W. (2008) Wingless signaling directly regulates cyclin E expression in proliferating embryonic PNS precursor cells. Mechanisms of Dev. 125, 857-64. NIHMSID # 71787.

Matakatsu, MT, and Du, W. (2008) Direct control of proneural gene atonal by retinal determination factors during Drosophila eye development. Dev Biol. 313, 787-801. PMCID: PMC2231519

Sukhanova, M. Deb, D.K., Gordon, G.M., Matakatsu, MT, and Du, W. (2007) Proneural bHLH proteins and EGFR signaling coordinately regulate cell type specification and cdk inhibitor expression in Drosophila.MCB, 27, 2987-96. PMCID: PMC1899942

Matakatsu, MT, Thomas, BJ, and Du, W. (2007) Mutation of the Apc1 homologue shattered disrupts normal eye development by disrupting G1 cell cycle arrest and progression through mitosis. Dev Biol.309, 222-235. (Epub 2007 Jul 14). PMCID: PMC2080841

Pogoriler J., Millen, K., Utset, M., and Du, W. (2006) Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development, 133, 3929-3937. (PMCID: PMC1868525)

Du, W. and Pogoriler, J (2006) Retinoblastoma Family Genes. Oncogene, 25, 5190-5200PMCID: PMC1899835)

Pogoriler, J and Du, W. (2004) Chk1 activation and the nuclear/cytoplasmic ratio.  Developmental Cell, 7, 147-148.

Duman-Scheel, M., Johnston, L., and Du, W. (2004) Repression of dMyc expression by Wingless promotes RBF-induced G1 arrest in the Presumptive Drosophila Wing Margin.  PNAS, 101, 3857–3862.

Weng, L., Zhu, C., Xu, J. and Du, W. (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development.  EMBO J., 22, 3865-3875.

Xu, J. and Du, W. (2003) Drosophila chk2 plays an important role in a mitotic checkpoint in syncytial embryos.  FEBS letter, 545, 209-212.

Duman-Scheel, M., Weng, L., Xin, S., and Du, W. (2002) Hedgehog signaling controls cell proliferation and growth through upregulation of Cyclin D and Cyclin E.  Nature, 417, 299-304.

Xin, S., Weng, L., Xu, J., and Du, W. (2002) The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth.  Development. 129, 1345-1356.

Xu, J., S. Xin, and W. Du. (2001). Drosophila Chk2 is required for DNA damage-mediated cell cycle arrest and apoptosis. FEBS Letters 508, 394-398.

Du, W. (2000) Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain.Development.  127, 367-379.